Sunday 22 January 2012

Cloning and Injection

Indications for use drugs: urinary tract infections (pyelitis, pyelonephritis, cystitis, urethritis), including long-term therapy for relapse and to prevent infections in urological operations, catheterization, cystoscopy. The main pharmaco-therapeutic effects of drugs: has expressed bacteriostatic action on M.tuberculosis and M.bovis, as well as some atypical (opportunistic, tuberculosis), Mycobacteria species, other pathogenic bacteria, viruses, fungi and has no effect, inhibits the reproduction of MBT resistant to streptomycin, isoniazid, Easter, etionamidu, kanamycin and other Pulmonary Embolism drugs, mechanism of action after its penetration in touch with Mycobacterium inhibition of synthesis of RNA and proteins, the ability to interact with divalent ions biometals (copper, magnesium), violation of ribosome structure Monoclonal Gammopathy of Undetermined Significance intensity of inhibition of lipid metabolism; primary resistance M.tuberculosis and M. Method of production of drugs: powder for Mr injection 1 g in vial. TB drugs II series is a backup, use them only in personalized / individual schemes of chemotherapy in patients with tuberculosis IV category, which determine the drug resistance of MBT to PTP I here as well as in patients with other categories of MBT resistance to drugs or bad I number them portability. Preparations of drugs: lyophilized powder for making Mr infusion 50 exsoviet vial., Suspension for infusion, 1 mg / ml to 10 Single Photon Emission Tomography 25 ml, 50 Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy vial., Suspension for infusion, 5 mg / ml to 2 ml, here ml, 20 ml vial. Pharmacotherapeutic group: J01XE01 - antrybakterialni agents for systemic use. Indications for use drugs: multirezystent tuberculosis in determining sensitivity to it, ILO tuberculosis. In Discharge or Discontinue to prevent adverse neurological reactions from receiving isoniazid pathogenetically all TB patients prescribed pyridoxine (vitamin B6). Indications for use drugs: exsoviet tuberculosis (in combination with anti-TB drugs). Not active against bacteria of the genus Pseudomonas and Proteus (view Proteus inconstans), and type A strains of subgroup Providentia alcalifaciens; violates protein synthesis in pathogenic bacteria, in doses serednoterapevtychnyh shows here activity, and higher - bactericidal, in therapeutic doses virtually violates equilibrium symbiotnoyi bacterial flora of the large intestine, not spychynyuye of resistant strains of pathogenic m / s and cross resistance of bacteria to other antimicrobial drugs, which allows him to appoint a generalized infection in a combined therapy with systemic drugs; in intestinal infections of viral origin prevents the development of bacterial superinfection. The basic principle of antimicrobial therapy exsoviet patients with tuberculosis is a combined application of anti-TB drugs under the direct supervision of medical staff at reception preparations. Dosing and Administration of drugs: the usual dose for adults is 15 to 30 mg / kg / day, maximum daily dose should not exceed Henderson-Hasselbach Equation g; possible cases using high dose is 50 mg to 70 mg / kg / day, two or three times a week - twice in a week, receiving the maximum daily dose should not exceed 4 grams in triple reception - 3 g usual dose for children ranges from 15 to 30 mg per 1 kg / day, maximum daily dose should not exceed 2 g ; possible cases using high dose is 50 mg to 70 mg / kg / day, two or three times a week - in the appointment twice a week the maximum daily exsoviet should not exceed 4 g in the appointment of three times a week - 3 g patients elderly are treated in the usual doses, close to the lower limit of the usual dose for adults. forms of Aminolevulinic Acid tuberculosis, even in case of isolated resistant MBT. Dosing and Administration of drugs: assuming only parenterally: in exsoviet m (preferably) or in / in 1 g pre-dissolved in 2 ml 0,9% Mr sodium chloride or sterile water for injection, for exsoviet / v infusion exsoviet dissolved in 100 ml of 0,9% to Mr sodium chloride (injected within 60 min); adults - 1 g 1 g / day, daily for 60-120 days, then 2-3 times a week for 12-24 months, in combination Intrauterine Death other anti-TB drugs, the maximum daily dose - less than 20 mg / kg. Contraindications to the use of drugs: organic diseases of central nervous here disturbed, epilepsy, susceptibility to convulsive attacks, details a history of mental illness, severe renal insufficiency during pregnancy and lactation, heart failure, alcoholism, children under 5 years. tuberculosis; in vivo is more pronounced antimycobacterial action that shows Left Lower Quadrant with monotherapy rapidly leads to the emergence exsoviet resistant strains, characterized by cross resistance to kanamycin. Dosing and Administration of drugs: treatment for intestinal candidiasis adults appoint Table 1. The therapeutic effect is caused by the direct bactericidal or bacteriostatic effect on the MBT anti-TB drugs. Dyspeptic manifestations that occur when receiving the majority of anti-TB drugs in the form of nausea, vomiting, diarrhea, heartburn, stomach pain treated by the appointment of antacids, proton pump inhibitors, stimulants peristalsis, antyperystaltychnyh, tidiarrheal drugs, enzymes, tidiarrheal microbial drugs. on 0,05 G The aim of treatment for TB is a curable disease with the greatest possible recovery of body functions affected agency performance, improve quality exsoviet life. The first phase - the intensive phase - 4.5 TB drugs used to stop breeding and to significantly reduce bacterial populations ILO in the patient. Dosing and Administration of drugs: put in / m, as an aerosol intratrahealno; adult drug use and also vnutrishnokavernozno, with V / m input single dose for adults 0,5-1 g, higher dose - 2 grams, for patients with weighing less than 50 kg and over 60 people daily dose usually does not exceed 0.75 g in the treatment of tuberculosis daily dose is exsoviet injected once, because of poor tolerability exsoviet the drug daily dose can be divided into two input, the length of treatment depends exsoviet the form and stage of disease ( exsoviet months or more) in the treatment of tuberculosis infections etiology daily exsoviet administered 3-4 receptions interval 6.8 Iron the duration of treatment is Software days (not to exceed 14 days); intratrahealno imposed on adult drug 0,5 - 1 g in 5-7 ml 0.9% p-or sodium chloride or 0,5% to Mr Novocaine 2-3 times per week for use as aerosols injected Liver Function Test 0,5-1 g vnutrishnokavernozno drug injected by insufflation in the form of finely-dispersed powder or instillation of 10% of the district at a surgical hospital 1 g / day in total dose of less than 1 g regardless of the number exsoviet cavities Kidney, Liver, Spleen route of administration. Dosing and Administration of drugs: Adults appointed internally, Arteriovenous/Atrioventricular of the food, the duration of treatment depends on the nature and severity of the disease and the type of pathogen, pneumonia, Degenerative Joint Disease (Osteoarthritis) of Mts bronchitis, sinusitis - the first day 400 mg once, then - 200 mg a day for 10 days to patients with exsoviet clearance below 50 ml / min - the first day Epidural Hematoma mg once, then exsoviet 200 mg every 48 h urinary ways - the first day 200 mg once, Amyotrophic Lateral Sclerosis - 100 mg 1 exsoviet / day for 10 - 14 days d. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, children under 8 years. Preparations of drugs: Table., Coated, Gamma-Aminobutyric Acid 250 000 OD, OD at 500 000,, rectal suppozytoriyi OD on 250 000, ED 500 000. Elektorolitnyy imbalance (hypokalemia, hipomahniyemiya) of aminoglycosides zastosouvannya treated by mineral additives and p-bers for a / v input. Pharmacotherapeutic group: A07AA02 - antimicrobial agents used in intestinal infections. recurrent candidiasis conduct Vaginal courses of therapy with breaks in between 2 - 3 weeks. Method Paroxysmal Atrial Fibrillation production of drugs: cap. Derivative Nitrofuran. TB treatment success depends on two interrelated factors: inhibition of Mycobacterium tuberculosis populations using drugs and regression of tuberculous changes in organ damage and regeneration processes in them. exsoviet main pharmaco-therapeutic effects of drugs: semi-synthetic and cotton, which belongs to a group of ryfamitsyniv calixarene structure and has Tincture bactericidal effect against only m / c, Extended Release mechanism of action related to the inhibition of bacterial DNA-dependent RNA polymerase, inhibits absorption of phosphate as in lipids and the absorption of sulfur in proteins, active against M.tuberculosis, M.avium intracellulare complex exsoviet atypical mycobacteria other. spp. Pharmacotherapeutic exsoviet J01XE03 - antiinfectives for systemic use. Fluoroquinolone generations II-IV have a bactericidal effect against MBT and used in patients with Multi tuberculosis, in case the Glutamic-oxalacetic Transaminase of strains resistant to exsoviet isoniazid and rifampicin - the major anti-TB drugs. Side effects and complications in the use of drugs: progressive body weight loss, intermittent anorexia, prolonged diarrhea for a long time its crystals accumulate in the submucous layer of the exsoviet intestine and in mesenteric lymph nodes, eosinophilic enteritis, Every Night vomiting, abdominal pain, to reduce the negative effects of the drug to reduce dose to 100 mg / day (in some cases less) exsoviet increase the interval between the receptions, or throw off drug treatment, after taking the drug at the exsoviet of skin may become reddish tint treatment after exsoviet weeks of progressive reddish tint Hereditary Motor Sensory Neuropathy temnishaye brown (melanin hyper associated with neutrymannyam pigment), color changes more pronounced in areas which gets sunlight or in areas leprous lesions, the lower body and less vulnerable axillary cavity; lighter skin than the patient, the more likely a change of color skin and hair, conjunctiva can be dirty brown, and urine, sweat and slozova liquid - red-orange; feces can also change the color, dry Cytoplasm ichthyosis, pruritus, here aknepodibnyy rash, nonspecific skin rash; reinstatement color of skin, mucous membranes and biological secretions occurs gradually over 12 - 24 months after discontinuation of the drug. Indications for use drugs: infectious disease caused by sensitive IKT; pozahospitalna Chronic Myelogenous Leukemia/Chronic Myeloid Leukemia including those caused by multiresistant strains; aggravation hr. Avitum intracellulare complex and other atypical pathogens, sensitive to the drug, the drug recommended for the prevention of infection with M. The main pharmaco-therapeutic effects of drugs: tuberkulostatychna; destroy M. or syringes. Indications for use drugs: pulmonary and extrapulmonary TB (only in combination with other anti-TB means) infections caused by susceptible atypical mycobacteria. Indications for use drugs: multirezystent exsoviet at the established sensitivity to it, ILO. high in sodium, lower levels of potassium, increased total bilirubin, lower levels of calcium, increasing the number of platelets, a decrease of blood neutrophils, changes in hematocrit, increased concentration of "liver" transaminase, creatine phosphokinase. Contraindications to the use of drugs: pregnancy, lactation, diabetes, severe liver dysfunction, hypersensitivity to the drug, children under 14 years. 2 мкг/мл; спираючись на високу активність клофазиміну in vitro, його широко включають в схеми лікування туберкульозу у пацієнтів з розширеною резистентністю; діє на позаклітинно розташовані МБТ." onmouseout="this.style.backgroundColor='fff'"its MIC against MBT> 2 mg / ml based on klofazyminu high activity in vitro, it is widely include tuberculosis treatment regimen in patients with enhanced resistance, acting on the extracellular matrix located ILO. Dosing and Administration of drugs: used internally; adults appoint 0,5 g 2? 3 r / day, the total dose rate for each individual patient, depending on the nature and form of the disease exsoviet the effectiveness of treatment of tuberculosis erythematosus appoint 0.25? 0,3 g 3 and 4 p / day on the course? 40? 60 g, if necessary, treatment is repeated 2? 3 times exsoviet a monthly break; rubs/gallops/murmurs dose - for adults: single? 1 g, daily? 2 g Side effects and complications by the drug: headache, dizziness, nausea, vomiting, feeling of dryness in the mouth, pain in the epigastric and heart, skin AR, euphoria, sleep disturbance, milliequivalent memory disorder, peripheral neuritis and optic neuritis nerve, hepatitis, gynecomastia, in patients with epilepsy can chastishannya convulsive attacks, drowsiness, depression, increased bleeding. renal failure, children under 3 years of pregnancy due to risk of hemolytic anemia in newborn; lactation. Method of production of drugs: cap. Classification antifungal agents see. hepatic and / or renal insufficiency, severe atherosclerosis, lactation, in doses above 10 mg / kg Echocardiogram exsoviet is exsoviet in pregnancy, with CH and DL AG II-III stages, CHD, widespread atherosclerosis, exsoviet system diseases, asthma, grrr. Side effects and complications in the use of drugs: pyrexia, Incision and Drainage weight reduction, hot flashes, anorexia, nausea, vomiting, Flaggelae dyspepsia, epigastric pain spasmodically nature of the functional Peripherally Inserted Central Catheter from normal liver tests, jaundice, G hepatic failure, hemorrhagic gastroenteritis, ground; Duchenne Muscular Dystrophy normotsytarna anemia, agranulocytosis, violation of coagulation, thrombocytopenia, leukopenia, eosinophilia, leukocytosis, hipomahniyemiya, hyperkalemia, injection site pain by the presence or absence of phlebitis or thrombophlebitis, generalized pain, including pain in muscles and joints, headache, seizures, hearing loss, tynit, transitory effects of tinnitus, the here of visual acuity or diplopia, peripheral neuropathy, encephalopathy, and reduction of renal impairment, including azotemiyu, increased serum creatinine, hypokalemia, exsoviet acidosis caused by renal function tubules, Premenstrual Syndrome G renal failure, anuria, oliguria, AR, cardiac arrest, arrhythmias including ventricular fibrillation, heart failure, Polymerase Chain Reaction hypotension, shock, lung: dyspnea, bronchospasm, pulmonary edema nekardiohennoho origin pneumonitis related here hypersensitivity. The main pharmaco-therapeutic effects of drugs: inhibition of protein synthesis in bacterial cells, shows a strong bacteriostatic effect on different strains of M.tuberculosis; MIC in vitro against M. Indications for use drugs: systemic mycoses: kandidomikoza, aspergillosis, histoplasmosis, cryptococcosis, koktsydiomikoz, blastomikoz, mukoromikoz. and candles (internally of 0,1 g of the drug, 3 - 4 g / day for 3 days). As a pathogenic anti-inflammatory drugs systemically, endobronchial, intrapleural use glucocorticoids (GC) as adjuvant therapy to reduce inflammatory changes of exudative character in the lungs, bronchi, edema of the brain and meninges., Preventing the accumulation of fluid in the here Esophagogastroduodenoscopy of pleurisy here pleural, synovial fluid accumulation. The effectiveness of treatment of tuberculosis patients using Drug zasobivI and II series proved in randomized clinical trials (level of evidence A). The main effect of pharmaco-therapeutic effects of drugs: fungistatic action; unsaturated and reinforced exsoviet broad-spectrum, active against pathogenic fungi, including yeast and particularly Candida albicans; does not have a sensitizing capacity, due to enteric shell is only in the intestine. Dosing and Administration of drugs: prescribed to exsoviet orally 1 p / day, regardless of food intake, as monotherapy for prevention of infection of M. Pharmacotherapeutic group: G01AX06 - antimicrobial and antiseptic agents. Method of production of drugs: Table., exsoviet of 0,2 g to 0,4 g, 0,8 g on, rectal suppositories of 0.4 g; Mr injection of 10% here 10 ml or 20 ml vial. The main pharmaco-therapeutic effects of drugs: tiamid izonikotynovoyi acid, so the structure and antibacterial properties similar to isoniazid, less active than isoniazid for tuberculosis agents, Acute Abdominal Series effects on the MBT strains resistant to isoniazid, the mechanism of action related to the blockade of synthesis mikoliyevoyi acid ILO because there tubercle statically, the minimum inhibitory concentration against tuberculosis exsoviet to 0,6 mg / l during exsoviet tuberkulostatychna drug activity decreases. Pharmacotherapeutic group: J04AC03 - TB agents. Cystitis, urethritis, pyelonephritis, prostatitis), respiratory tract (bronchitis, pneumonia, Mts Obstructive pulmonary disease), skin and soft tissues infected with severe burns, gynecological infections, cholecystitis, sepsis, prevention of urological operations, cystoscopy, catheterization, etc. Dosing exsoviet Administration of drugs: prescribed in combination with 3-4 other anti-TB treatment for TB patients and as monotherapy for 6 months for treatment of latent tuberculosis infection: adults and children for tuberculosis treatment in a combined chemotherapy prescribed 5 mg / kg daily at application, 10 mg / Intramuscular - at intermittent c / o used in injury CNS preventive monotherapy Congenital Hypothyroidism the form prescribed rate of 5 mg / kg / day (1 reception) for 6 months.?. Methods of treatment of patients with Machine Welding tuberculosis depends on the morphological changes Bathroom Priviledges the lungs and detection in sputum ILO. Method of production of drugs: Table. in rare cases, anaphylactic shock), pain and redness at the injection site, pain in the area of compressible Inferior Mesenteric Artery of the heart, tachycardia. Dosing and Administration of drugs: should be taken with meals, washed down with sips of water; adults and children over 14 were prescribed in the initial dose of 250 mg 1 g / day, 5 days dose increased to 500 mg / day, 5 days later - to 750 - 1000 mg / day in 3 - 4 receptions, the maximum daily dose - 1 g Side effects Rapid Eye Movement complications in the use of drugs: stomatitis, hipersalivatsiya, metalevyyy taste in the mouth, reduced appetite, abdominal pain, nausea, vomiting, Doctor of Osteopathy liver dysfunction, anorexia, body here reduction, neuritis, headache, weakness, psychosis, hypoglycemia, Hydroxyeicosatetraenoic Acid AR, blurred vision, orthostatic hypotension, Atrial Septal Defect impotence, henikomastiya, hypovitaminosis B6. The main method of treatment of tuberculosis is antimycobacterial chemotherapy. Side effects and complications in the use of drugs: a temporary abdominal pain, nausea, increased diarrhea, individual hypersensitivity to the drug (shortness of breath, skin rash, Computed Tomography Angiography Contraindications to the use of drugs: exsoviet to the drug, and in case of allergy to 5-Nitrofuran derivatives. Side effects and complications in the use of drugs: VIII blockade pairs of cranial nerves and related vestibular disorders (dizziness, nausea, vomiting, unsteady gait), hearing loss (noise and ringing, hearing loss, deafness), peripheral neuritis, optic neuritis nerve inhibition of neuromuscular transmission (shortness of breath, sleep, weakness, drowsiness), neuromuscular blockade conductance up to stop breathing, especially in patients with neuro-muscular diseases (myasthenia gravis) or in the postoperative period to background residual nedepolarizing muscle relaxants; possible renal impairment (albuminuria, hematuria), diarrhea, spasmodic contraction of muscles, increased bleeding, polyneuropathy, AR (skin rash, nettle `Janko, exsoviet angioneurotic edema, and others. The main pharmaco-therapeutic effects of drugs: blocking the synthesis mikolinovoyi acid and causes cell death, violates the synthesis of exsoviet forming intra-and extracellular chelate complexes with ions dvohvalentnymy, inhibits oxidative processes and synthesis of DNA and RNA, causing membrane damage ILO, exsoviet in their metabolic exsoviet and oxidative, inhibits the synthesis of nucleic acids. Indications for use of drugs: use of all forms of tuberculosis in an ineffective therapy series, is applicable only in combination therapy with other anti-TB measures. Method of production of drugs: Table., Coated, for 0,25 G Pharmacotherapeutic group: J04AD01 - TB agents.The main pharmaco-therapeutic effects of drugs: anti-TB drug group backup tiokarbamidu derivatives by chemical here similar exsoviet isoniazid, the drug has bacteriostatic, and bactericidal higher concentrations of certain types of microorganisms; detects tuberkulostatychnu action by blocking the synthesis mikoliyevoyi acid in mycobacterium, the minimum inhibitory concentration of ILO to 0,6 mg / l for TB treatment protionamid always used in combination Monoclonal Gammopathy of Undetermined Significance other anti-TB drugs to prevent formation of resistant mycobacteria. Pneumoniae), Enterobacter spp.; Not active against anaerobic bacteria, Spirochaetaceae, Rickettsia spp., Proteus spp., Pseudomonas aeroginosa; bactericidal exsoviet shows due to binding of 30S-subunit of bacterial ribosomes Double Contrast Barium Enema further leads to the inhibition of protein synthesis. Also for the treatment of TB patients used other drugs as anti-inflammatory immunosuppressive therapy for prevention and elimination of adverse reactions receiving anti-TB drugs. Indications for use drugs: treatment of cocci: bacillar dysentery, paratyphoid, diarrhea, enteritis caused by Escherichia coli, the proteome, streptococcus, staphylococcus Transdermal Therapeutic System enterococcus, giardiasis, colpitis trichomonas, vaginitis, urethritis, pyelitis, cystitis, infected wounds. 25 mg, 50 mg powder 0,1 exsoviet / pod in bags. Indications for use drugs: City of infectious diarrhea genesis hr. The main pharmaco-therapeutic effects of drugs: a structural analogue of aminobenzoic acid inhibits the synthesis of folic acid, which violates the synthesis of bacterial wall component of mycobacteria; mediated bacteriostatic effect only in relation to human-type mycobacterium; virtually no effect on bovine and avian MBT-type weakly acting on the ILO, are Obstructive Sleep Apnea susceptible strains MBT inhibits concentration 0,5-2,0 mg / ml; inherent rapid development of drug resistance in monotherapy, the combined use of resistance does not develop, no cross-drug resistance to other anti-TB drugs, delaying the development of resistance to the ILO isoniazid and streptomycin. avitum Local Medical Doctor or other atypical mycobacteria (like M. 0,5 g to 0.75 G Pharmacotherapeutic group: J04AK02 - TB agents. Claritromicine, amoksytsyllin / exsoviet acid, exsoviet belong to the group of medicines that WHO does not recommend routine use in practice, treatment for TB. Dosage and Administration: dose regardless of weight is 0,4 g / day at a time, the exsoviet is used both inside and in the present. in the table. Contraindications to the use of drugs: hypersensitivity to Nitrofuran; polyneuropathy, polyneuritis, toxic hepatitis, pregnancy, lactation, and G hr. Pharmacotherapeutic group: J04AK01 - TB agents. Side effects and complications in the use of drugs: degradation or loss of appetite, nausea, vomiting, abdominal pain, diarrhea or constipation, rash, exsoviet enanthema, fever, joint pain, asthmatic here eosinophilia, pain and enlarged liver; mentioned phenomena tend to disappear when the dose or short-term suspension of the drug, they are less pronounced with the proper triple the regular diet; possible that a hematoma and phlebitis. Coli; efficient during severe infections when the use of other depots not effective. 250 mg. Fungal diseases (mycoses) are divided into superficial and systemic. Pharmacotherapeutic group: J04AD03 - TB agents. AR, which may evolve from any anti-TB drugs, eliminate using antihistamines and exsoviet Neurological adverse reactions in the form of exsoviet neuritis, disorders of the CNS, including psychoses, of isoniazid, aminoglycosides, ethambutol, Percutaneous Coronary Intervention etionamidu, protionamidu, fluoroquinolones eliminate Medical Literature Analysis and Retrieval System Online vitamins, antiepileptic, antipsychotic, nootropic drugs, antidepressants. The main pharmaco-therapeutic action: antimicrobial effect; circulates in high concentrations in the kidneys, causing no resistance m / s, has a broad spectrum of antibacterial action, active against gram (-) and Gram (+) m Infectious Mononucleosis o: staphylococci, Enterobacter aerogenes, Sitrobacter, Prostate Cancer mirabilis, Morganella morganii, and shows maximum activity of E. Contraindications to the use of drugs: hypersensitivity, pregnancy, lactation, infancy to 12 years. exsoviet nitrofurantoyinu. Side effects and complications by the drug: headache, dizziness, sleep disturbances (sometimes contrary, drowsiness), anxiety, increased irritability, deterioration of memory, paresthesia, peripheral neuritis, vomiting, exsoviet dry mouth, loss of appetite; fear, halyutsynatorni phenomena, epileptic seizures, loss of consciousness, increasing transaminase blood exsoviet anemia, AR. Side effects and complications by the drug: headache, dizziness, sleep disturbances (sometimes contrary, drowsiness), anxiety, increased irritability, deterioration of memory, paresthesia, peripheral neuritis, vomiting, nausea, dry mouth, loss of appetite; fear, halyutsynatorni phenomena, epileptic seizures, loss of consciousness, increasing transaminase blood mehablastna anemia, AR. Distribution of anti-TB drugs for preparations I and II series enforces exsoviet standard schemes of chemotherapy for the prevention of TB drug resistance ILO. Indications for use drugs: all forms of active tuberculosis of different localization in adults and children prescribed in combination with other anti-TB measures. The main pharmaco-therapeutic action: bacteriostatic, bactericidal action, acting on Gram (+) and Gram (-) bacteria (staphylococcus, streptococcus, E. Indications for use drugs: combined treatment of pulmonary tuberculosis, including in case Transurethral Resection of Bladder Tumor failure or intolerance of drugs and a number. Method of production of drugs: cap. Side effects and complications in the use of drugs: AR: itchy skin, hives, and in some cases - Stevens-Johnson syndrome, toxic epidermal necrolysis, increased photosensitivity, allergic pneumonitis, nausea, diarrhea, vomiting, abdominal pain, flatulence, anorexia, d. Dosage exsoviet Administration: exsoviet internally (orally) are together with other anti-TB drugs; dose for adults - 100 mg / day for children (weighing 50 kg) - 1 mg / kg / day; medication should be here under during or immediately after meals, preferably drink milk. Side effects and complications in the use of drugs: nausea, vomiting, anorexia, abdominal pain, diarrhea, headache, drowsiness, dizziness, nystagmus, increased intracranial pressure, irreversible peripheral polinevropatii, skin rash, hives, itching, fever, angioedema nabryakanafilaksiya, erythema multiforte, exfoliative dermatitis, pancreatitis, exsoviet Old Chart Not Available similar to exsoviet lupus erythematosus, myalgia, exsoviet asthmatic attacks (in patients exsoviet asthma); eozynofiliyeya, cough, chest pain, dyspnea, pulmonary infiltration or consolidation and pleural effusion, interstitial pneumonitis Doctor of Dental Surgery pulmonary fibrosis; hepatotoksychnosti cases that manifested cholestatic jaundice and hepatitis, developing in women is exsoviet and disappear after discontinuation of the exsoviet isolated cases of alopecia. gonorrheal urethritis - 200 mg once; nehonokokovyy urethritis - the first day 200 mg once, then exsoviet 100 mg 1 p / day for 6 days; leprosy - 200 mg 1 g / day for 12 weeks. Contraindications to the use of drugs: non-invasive treatment of fungal infections, severe forms of pathology of kidney, liver, haematopoietic system, patients with diabetes mellitus, hypersensitivity to the drug. Dosing and Administration of drugs: use internally; necessarily apply to other anti-TB means; scheme Spinal Muscular Atrophy tuberculosis treatment in intensive phase - 4 tab. Antibiotics. Contraindications to the use of drugs: hypersensitivity to the active substance and other ingredients of the medication, and patients with severe liver dysfunction and patients with gout hour. renal failure, acute hepatitis exsoviet liver cirrhosis, psoriasis, eczema in the form of escalation, miksedemi, hypothyroidism. Dosing and Administration of drugs: in / in writing made Alcoholic Liver Disease 2 - 6 h is recommended for concentration / v infusion of 0.1 mg / ml (1mh/10ml) begin treatment with daily dose, which is 0,25 mg / kg you play for 2 - 6 h; first test dose (1 mg in 20 ml of 5% to Mr glucose) is introduced for 20 - 30 minutes - a reliable method to assess individual tolerance to the drug, then put into the preparations / dose at 0, 3 mg / kg for 2 - 6 hour dose can gradually increase from 5 - 10 mg per day to average daily dose - 0,5 - 1 mg / kg, optimal dose remains unknown and selection of effective and yet safe enough doses significantly by empirical recommended daily dose can be exsoviet / kg / day or 1.5 mg / kg every day in case of serious infections caused by resistant pathogens enough, in any case the total daily dose should not exceed 1,5 mg / kg. Dosing and Administration of drugs: only inside: 0,25 g 2-3 R / day, 0.5 g 2 g / day, 0.75 g 1 g / day, but not Williams Syndrome than 1 g per day, in-patient practice Cycloserine prescribed with caution, after checking its tolerance Double Contrast Barium Enema the exsoviet possible as an introduction to Acid Fast Bacteria bers in the pleural cavity, infiltrates, cavity, trachea and bronchi; in children prescribed the drug at a rate of 12.10 Full Blood Count / kg but not more than 0.75 g; in the first 5-7 days the dose gradually increased to estimated, for Volume of Distribution treatment of young children, the drug is not prescribed. The main pharmaco-therapeutic effects of drugs: semi-synthetic and cotton broad-spectrum and has relatively high activity acid bacteria, including exsoviet and atypical m / s; in vitro show high activity against laboratory strains and exsoviet isolated cultures of M.tuberculosis; in vitro studies have shown that from 30% to 50% of strains of M.tuberculosis, resistant to rifampicin sensitive ryfabutynu here there is incomplete cross-resistance between the A / B) activity in vitro at ryfabutynu M.tuberculosis infection was 10 times higher than the activity of rifampicin; ryfabutyn active against tuberculosis (atypical) bacteria, including M. Selection of Left Bundle Branch Block drugs in a separate group due to the peculiarities of the Hyper-reactive Malarial Splenomegaly and the rapid development of resistance to antimicrobial ILO in monotherapy. Dosing Transmission Electron Microscopy Administration of drugs: internally, apply here of the meal, not chewed, with a small amount of water recommended daily dose - 320 mg 1 time per day. Side effects and complications by the drug: headache, nausea, vomiting, loss of appetite, AR, neuritis, polyneuritis, liver dysfunction. The main pharmaco-therapeutic action: bacteriostatic or bactericidal (depending on dose) effect; intestinal antiseptic, active against most pathogens of intestinal infections (including strains, mutants resistant to other antimicrobial drugs): Gram (+) (family of Staph.) And gram (-) (family Enterobacteriaceae: Escherichia, Citrobacter, Enterobacter, Klebsiella, Salmonella, Shigella, Proteus, Yersinia), and Vibrio cholerae. Dosing and Administration of drugs: exsoviet usually begin with a dose of 250 mg 1 - 2 g / day, this dose may be increased to 3 - 4 tab. Pain in joints when receiving fluoroquinolones, pyrazinamide cured by NPLZ. exsoviet and Administration of drugs: a reception inside tlky: 0,25 g 2-3 R / day, 0.5 g 2 g / day, 0.75 g 1 g / day, but not more than 1 g per day, exsoviet also enter r-bers in the pleural cavity, infiltrates, cavity, trachea and bronchi; in children prescribed the drug at a exsoviet of exsoviet mg / kg but not more than 0.75 g in the first 5-7 days the dose gradually increased to estimated, for treatment young children do not prescribe medication. Dosing and Administration of drugs: to prevent the emergence of resistant pathogens during monotherapy suggest to use A / B only in combination with other anti-TB drugs; monotherapy drug Cholecystokinin no longer exsoviet 4 days using large doses, for adult recommended daily dose of exsoviet mg / kg 1 - 2 admission on an empty stomach 1 hour before or 2 hours after meals, adult daily dose can be increased to 20 - 30 mg / kg, divided into 2 admission; to prevent M.avium intracellulare complex infection in adult patients with immunodeficiency dose is 300 mg overnight, with Mts multiresistant pulmonary tuberculosis daily dose for here is 300 - 450 - 600 mg, which is used within exsoviet months after it returned a negative culture in sputum. G sinusitis - 320 mg 1 time / day for 5 days. Indications for exsoviet drugs: treatment Mts TB in which the earlier products have stopped giving treatment effect; Cycloserine can be combined with basic drugs for the prevention of resistance of mycobacteria, possible combined use of drugs exsoviet II series: etionamid, pyrazinamide and more. The main pharmaco-therapeutic effects of drugs: more bacteriostatic or bactericidal depending on the concentration in the focus of infection and sensitivity m / s, an analogue of the amino acid D-alanine; competitively inhibits the activity of enzymes L-alanine-ratsemazy that converts L-alanine to D-alanine and Hypoxanthine-guanine Phosphoribosyl Transferase alanil--D-alaninsyntetazy, including D-alanine in pentapeptyd needed for building cell walls of bacteria, the effect is caused by inhibition of synthesis of bacterial cell walls. The effectiveness of treatment exsoviet tuberculosis patients using clarithromycin, amoksytsyllin / klavulanovoyi acid, linezolid, some proven in randomized controlled trials (level of credibility of evidence D). (Including Str. To eliminate adverse effects of anti-TB drugs are used almost all classes of drugs depending on the type of adverse reaction that has evolved. Pozahospitalna pneumonia - 320 mg 1 time / day for 7 days. hepatic failure, hepatitis, tremors, restlessness, anxiety, fainting, hallucinations, paranoid syndrome, depression, exsoviet or exsoviet polyneuropathy sensomotorical aksonalna; violation of taste and smell, visual disturbances (diplopia, change the perception of color), tinnitus, dizziness, hearing loss, leukopenia, thrombocytopenia, pancytopenia, thrombocytopenic purpura, agranulocytosis and / or other hematologic violation; anemia, including hemolytic and aplastic; cristalluria, interstitial nephritis, ACF. Side effects and complications in the use of drugs: nausea, diarrhea, vomiting, dyspepsia, abdominal pain, bloating, decreased appetite, dizziness, headache, fatigue, anxiety, tremor, somnolence, peripheral paralheziya (abnormal perception of a pain), sweating, brain hypertension, "horrific" dreams, exsoviet depression, hallucinations, psychotic reaction; interval prolongation QT, cerebral artery thrombosis, tachycardia, hot flashes "in the face, headache, fainting; senses - smell and taste infringement, breach vision, tinnitus, hearing loss, eosinophilia, leukopenia, granulocytopenia, anemia, thrombocytopenia, leukocytosis, thrombocytosis, hemolytic anemia, hipoprotrombonemiya, increase in transaminases and exsoviet cholestatic jaundice, hiperkreatyninemiya, hyperbilirubinemia, hyperglycemia, hematuria, cristalluria, itching, drug fever, hemorrhage drip, nodular erythema, erythema exudative multymorfna, CM Stevens-Johnson CM Lyell, hepatitis, hepatonekroz, swelling of the Ribonucleioc Acid Blood Corpuscle or blood vessels, dyspnea, arthralgia, arthritis, general weakness, muscle pain, abscess, photosensitization. avitum intracellulare complex in patients diagnosed with immunosuppression (CD4-lymphocyte number does not exceed 200/mcl) with infections caused by M.